By American College of Chest Physicians
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Additional info for ACCP pulmonary medicine board review
There is added importance for prophylaxis when one considers that most patients who die of PE do so within 30 min of the acute event. The strategy used for the prevention of DVT and PE should be based on the patient’s level of risk, as suggested by the American College of Chest Physicians Consensus Conference on Antithrombotic Therapy. indd 27 27 7/10/09 8:03:54 PM factors include advanced age, history of VTE, cancer, stroke with lower-extremity weakness, endstage renal disease, and bed rest. Many medical patients have multiple risk factors.
Ann Intern Med 2008; 148:278−283 A short, easily understandable description of the discovery and meaning of genetic predispositions to the development of PAH. Quinlan DJ, McGuillan A, Eikelboom JW. Lowmolecular-weight heparin compared with intravenous unfractionated heparin for treatment of pulmonary embolism: a meta-analysis of randomized, controlled trials. Ann Intern Med 2004; 140:175−183 LMWH appears to be similar to UFH in safety and efficacy for the treatment of either symptomatic or asymptomatic PE.
Chest 2004; 125:509–521 This eight-center CF gene therapy study determined the safety of repeated doses of aerosolized adeno-associated vector containing CFTR complementary DNA. It showed that the aerosolized viral vector encoding the complete human CFTR DNA was safe and well tolerated. There were trends in improvement in pulmonary function in patients with CF and mild lung disease. Nichols DP, Konstan MW, Chmiel JF. Anti-inflammatory therapies for cystic fibrosis-related lung disease. Clinc Rev Allerg Immunol 2008; 35:135–153 Comprehensive and up-to-date review of the inflammatory mechanisms in CF.
ACCP pulmonary medicine board review by American College of Chest Physicians