Download e-book for kindle: Aestivation: Molecular and Physiological Aspects by Philip C. Withers, Christine E. Cooper (auth.), Carlos

By Philip C. Withers, Christine E. Cooper (auth.), Carlos Arturo Navas, José Eduardo Carvalho (eds.)

ISBN-10: 3642024203

ISBN-13: 9783642024207

ISBN-10: 3642024211

ISBN-13: 9783642024214

Numerous animal species dwell in environments characterised by way of a seasonal relief within the availability of water, which regularly yet no longer continually happens while temperatures are maximum. for lots of such animals, survival throughout the hardest season calls for spending lengthy classes of time in a slightly inactive country referred to as aestivation. yet aestivation is far greater than final inactive. profitable aestivation calls for the choice of a formal microhabitat, variable levels of metabolic arrest and responsiveness to exterior stimuli, the power to feel the right kind time of yr for emergence, the maintenance of inactive tissue, and masses extra. So, aestivation consists of a posh number of behaviors, ecological institutions and physiological changes that modify throughout species of their variety, value and direction. This booklet seeks to discover the phenomenon of aestivation from various views and degrees of association, starting from microhabitat choice to genetic regulate of physiological alterations. It brings jointly authors from the world over engaged on assorted systematic teams, ways, and questions, yet who're all eventually operating to raised comprehend the complicated factor of aestivation.

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2) and foot muscle of aestivating O. lactea (Ramnanan et al. 2009). This means an increase in the amount of eIF4E bound to 4E-BP1 during estivation and is again indicative of translational inhibition in the hypometabolic state. Translation is also regulated at the level of peptide elongation and several protein kinases focus their attention on the eukaryotic elongation factor 2 (eEF2) with phosphorylation inhibiting the factor (Browne and Proud 2002). This protein is also a target for phosphorylation in O.

Citrate decreased by 35%). Ion exchange chromatography revealed two peaks of activity that were identified as low and high phosphate forms; the low phosphate form dominated in active snails (57% of total activity) and the high phosphate form in aestivation (71%). PKG and protein phosphatase 1 (PP1) appeared to be responsible for the interconversion of the two forms. The high phosphate form of G6PDH was also less sensitive to urea inhibition and more resistant to thermolysin proteolysis; this suggested greater structural stability which could be advantageous during long-term dormancy.

Compiled from Ramnanan et al. (2009) 2 Metabolic Regulation and Gene Expression During Aestivation 33 phospho-eIF4GI (Ser1108) decreased strongly in hepatopancreas during aestivation. Similarly, the content of phospho-eIF4E (Ser209) decreased strongly in foot muscle after 14 days of aestivation (Ramnanan et al. 2009). Reduced phosphorylation of both proteins is consistent with translational inhibition during aestivation. Furthermore, eIF4E is closely regulated by reversible association with a specific binding protein, 4E binding protein (4E-BP1).

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Aestivation: Molecular and Physiological Aspects by Philip C. Withers, Christine E. Cooper (auth.), Carlos Arturo Navas, José Eduardo Carvalho (eds.)


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